Association of thymidylate synthase gene 3'-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLC

Table 1 Association of TS protein expression with clinicopathological data from patients with NSCLC

Characteristic	n	Positive expression of TS protein	Positivity (%)	χ²	P
Age (years)
< 60	72	45	63	1.1	0.29
≥ 60	88	62	70	1.1	0.29
Gender
Male	84	51	61	3.0	0.08
Female	76	56	74
Disease stage
IIIB	108	75	69	1.0	0.32
IV	52	32	62	1.0	0.32
ECOG grade
0	48	28	58	2.4	0.31
1	74	53	72
2	38	26	68
Histology
Squamous cell carcinoma	41	34	83	6.4	0.01
Adenocarcinoma	119	73	61

ISSN: 1423-0127