Fig. 4
WJMSC-EVs reduce lung injury and improve the survival of ALI. A Survival rate of sham, ALI rats, ALI treated with 2 × 1010 EV-Ctrl, or ALI treated with 1 × 1011 EV-Ctrl. B Evaluation of lung histology by hematoxylin and eosin staining. Scale bars = 500 μm. (n of sham, ALI, 2 × 1010 EV-Ctrl, 1 × 1011 EV-Ctrl = 6, 7, 9 and 10 rats, respectively). C Lung injury scores were assessed. D The measurement of let-7a-5p expression in the plasma using qRT-PCR. Data were presented as mean ± standard deviation. Statistical analyses were performed using a two-tailed unpaired Student’s t-test. (*p < 0.05, **p < 0.01, ***p < 0.001, ns = non-significant)