Journal of Biomedical Science is supported by the National Science and Technology Council (NSTC), Taiwan.
Hesperetin promotes longevity and delays aging via activation of Cisd2 in naturally aged mice
The human CISD2 gene is located within a longevity region mapped on chromosome 4q. In mice, Cisd2 levels decrease during natural aging and genetic studies have shown that a high level of Cisd2 prolongs mouse l...