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Figure 1 | Journal of Biomedical Science

Figure 1

From: Distinct population of highly malignant cells in a head and neck squamous cell carcinoma cell line established by xenograft model

Figure 1

Establishing HNSCC cell lines with increased malignant potential by the xenograft model. (A) Experimental strategies for the generation of HNSCC cell lines with increased malignant potential. The solid tissue from the tumors produced by implantation of SAS-GFP, SASVO1 and SASVO2 cells was mechanically and enzymatically disaggregated into single-cell suspension, and designated as SASVO1, SASVO2 and SASVO3, respectively. In vivo GFP imaging of the tumors was carried out and the tumors were measured using an illuminating device. Pictures shown are from mice at 28 day post-injection. (B) Tumor growth of the xenograft-derived SAS cells in the nude mice. Tumors volumes were determined twice weekly. Data shown are the means ± SD.

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