Viral and host proteins involved in picornavirus life cycle

Table 1 Cellular proteins involved in picornaviral RNA replication

Proteins	Binding sites/associated viral proteins	Viruses	Refs
PCBP1	Cloverleaf	PV	[93, 95]
PCBP2	Cloverleaf, 3CD, 3C	PV	[92, 93, 106]
hnRNP C	Negative strand 3' stem-loop I, 3D, 3CD, P2, P3	PV	[97]
hnRNP K	5' UTR	EV71	[96]
Sam68	3D	PV, CVB3	[105, 169]
PABP	3CD, stem-loop I and poly(A) tail	PV	[106, 107]
OCT-1	3CD, 3C	PV, HRV16	[19, 23]
B23	3CD	HRV16	[19]
La	3' and 5' UTR	CVB3	[112]
EF-1α	3CD, stem-loop I	PV	[91]

*PCBP, poly(rC) binding protein; hnRNP, heterogeneous nuclear ribonucleoprotein; PABP, poly(A)-binding protein; La, Lupus autoantigen; EF-1α, eukaryotic elongation factor 1 alpha.

ISSN: 1423-0127