Molecular events associated with epithelial to mesenchymal transition of nasopharyngeal carcinoma cells in the absence of Epstein-Barr virus genome

Table 2 Comparison of immunophenotypic features of NPC-BM1 cells and the original bone marrow aspirate

Monoclonal antibody	Xenograft (section)	Bone marrow aspirate (cytospin)
HLA-A, B, C	++++*	++++
HLA-DR	++ (focal)	++ (scattering)
NMIgG	-	-
PBS	-	-
EMA	+++	+++
AE1	++	++
CK7	++++	++++
EpCAM (EPS)	++++	++++
Le^y	-	-

Immunostaining of the SCID mouse xenograft resulting from s. c. injection of NPC-BM1 cells and the original bone marrow biopsy (cytospin cells) from which the NPC-BM1 cell line was established.
*Results are expressed by the extent of immunostaining on tumor cells. See the footnote of Table 1 for the abbreviations of the markers tested.

ISSN: 1423-0127