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Table 2 Comparison of immunophenotypic features of NPC-BM1 cells and the original bone marrow aspirate

From: Molecular events associated with epithelial to mesenchymal transition of nasopharyngeal carcinoma cells in the absence of Epstein-Barr virus genome

Monoclonal antibody Xenograft (section) Bone marrow aspirate (cytospin)
HLA-A, B, C ++++* ++++
HLA-DR ++ (focal) ++ (scattering)
NMIgG - -
PBS - -
EMA +++ +++
AE1 ++ ++
CK7 ++++ ++++
EpCAM (EPS) ++++ ++++
Ley - -
  1. Immunostaining of the SCID mouse xenograft resulting from s. c. injection of NPC-BM1 cells and the original bone marrow biopsy (cytospin cells) from which the NPC-BM1 cell line was established.
  2. *Results are expressed by the extent of immunostaining on tumor cells. See the footnote of Table 1 for the abbreviations of the markers tested.