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Table 2 Comparison of group-specific motifs identified in this study to the PROSITE motifs.

From: Identification of group specific motifs in Beta-lactamase family of proteins

A)
Group Pattern Sensitivity Specificity
A S-[DG]-N-x(1,2)-A-[ACGNST]-x(2)-[ILMV]-x(4)-[AGSTV] 70.270 99.048
B H-x-[DEH]-x-D-H 82.556 100
C S-x-[AEGQST]-K-x(2,4)-T 80.851 90.297
D S-T-[FY]-K-[IV]-x(2)-[AST]-[LMV]-[FILM]-[AG]-x-[ADEQS]-x(3)-[ILV] 71.429 97.561
E D-[IV]-R-x(3)-E 80.435 88.095
F G-x(2,3)-F-x-[GST]-x-[QST]-D-x(1,2)-E-[IV]-[IL]-[AIL]-x-[GL]-x-[AES] 87.5 100
B)    
Class Pattern Sensitivity Specificity
A [FY]-x-[LIVMFY]-{E}-S-[TV]-x-K-x(3)-{T}-[AGLM]-{D}-{KA}-[LC] 42.4 97.5
B [LI]-x-[STN]-[HN]-x-H-[GSTAD]-D-x(2)-G-[GP]-x(7,8)-[GS] 1.8 100
C [FY]-E-[LIVM]-G-S-[LIVMG]-[SA]-K 7.5 69
D [PA]-x-S-[ST]-F-K-[LIV]-[PALV]-x-[STA]-[LI] 41.1 100
E Information not available   
E Information not available   
  1. A) Group-specific motifs identified in this study. B) Motifs available in PROSITE database for class A, B, C and D lactamases