Figure 5

Control of infectious abortion by protein interaction via the EEVD motif of Hsc70. Infectious abortion was prevented by blocking the EEVD motif of Hsc70. Pregnant mice were inoculated with R2-25, rat IgG (control), TPR-Ba and immunized with EEVD or sEEVD (CAPISEDGSGETV) peptides. Control received no treatment. Statistically significant differences between the untreated control and antibody treated mice are indicated by asterisks (*, P < 0.01).