Increased expression of Matrix Metalloproteinase 9 in liver from NZB/W F1 mice received antibody against human parvovirus B19 VP1 unique region protein

Table 1 Mice infused with various rabbit antibody or reagent

	Antibodies or reagent infused into mice
	PBS [n = 6]	Control IgG [n = 6]	B19-NS1 [n = 6]	B19-VP1u [n = 6]
Body Weight (gram)	33.9 ± 1.7	33.9 ± 0.2	32.6 ± 2.5	33.6 ± 2.7
WBC (10³ cells/ul)	6.3 ± 0.7	5.5 ± 1.1	6.2 ± 1.6	4.3 ± 1.4
RBC (10⁶ cells/ul)	7.7 ± 0.6	8.7 ± 0.2	8.1 ± 0.2	7.8 ± 0.2
HGB (g/dL)	12.5 ± 1.1	15 ± 0.3	13.6 ± 0.5	13.3 ± 0.6
HCT (%)	44.2 ± 1.3	53.3 ± 2.2	50.4 ± 1.9	47.2 ± 1.4
MCV (fL)	57.3 ± 2.5	61.1 ± 1.1	62.3 ± 0.8	60.4 ± 0.9
MCH (pg)	16.2 ± 0.3	17.2 ± 0.2	16.9 ± 0.3	17.4 ± 0.6
MCHC (g/dL)	28.3 ± 1.7	28.2 ± 0.8	27.1 ± 0.2	28.3 ± 1.3
aPTT (second)	69.5 ± 8.1	76.4 ± 11.6	87 ± 6.0	156 ± 27.0* ^,#,¥
Platelet count (10³ cells/mm³)	1186 ± 219	1198 ± 124	1374 ± 179	808 ± 90.0* ^,#,¥

The unit of the parameter is presented in bracket.
NS1: non-structure protein 1; VP1u: VP1 unique region protein; WBC: white blood cell; RBC: red blood cell; HGB: Hemoglobin; HCT: Hematocrit; MCV: Mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: hemoglobin concentration; aPTT: activated partial thromboplastin time.
*, #, and ¥ indicate P < 0.05, as compared to the PBS, control IgG, or B19-NS1 group, respectively.

ISSN: 1423-0127