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Figure 3 | Journal of Biomedical Science

Figure 3

From: Telomerase prevents accelerated senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts

Figure 3

The karyotypes and anchorage-independent growth potential of hTERT-expressing normal and G6PD-deficient fibroblasts. The karyotypes of hTERT-expressing normal fibroblasts (T5) and G6PD-deficient fibroblasts (GT3) were determined as described in Materials and Methods; representative data are shown in panel A. Anchorage-independent growth was assayed by the ability to form colonies in soft agar. Representative results for hTERT-expressing G6PD-deficient fibroblasts are shown in panel B (right panel); no colonies formed and only single cells were detected. In HT1080 fibrosarcoma cell positive controls, colonies were detected (left panel).

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