Figure 4
From: Distinct functional defect of three novel Brugada syndrome related cardiac sodium channel mutations
Recovery from inactivation and develop of slow inactivation. (A) Recovery from inactivation (n = 10,11, and 8 for WT, p.R965C, and p.1876insM respectively). The currents recorded at P2 were normalized to that at P1 and were plotted against time. Two-exponential equation was used to fit the plot. (B) Develop of slow inactivation. Currents at P2 and P1 were normalized and plotted against time (n = 8, 10, and 6 for WT, p.R965C, and p.1876insM respectively). **, p < 0.01 when compared to WT using one way ANOVA followed by Tukey test