Table 2 Gene transfer immunostimulatory molecules.
From: Immunotherapy for liver tumors: present status and future prospects
Cytokine | Mechanism | Ref. |
|---|---|---|
IL-2 + IL-12 | CTLs | 149 |
IL-10 | CD8+ | 152 |
IL-12 | NK, CD4+, CD8+ | 187 |
IL-12 + IL-10 | NK, CD4+, CD8+, Macrophages, Neutrophils | 165 |
IL-2 | CTLs | 166 |
HLA-B7 | CTLs | 167 |
IL-12 + IP-10 | CD8+, CD4+, NK | 161 |
IL-12 + MIP3α | CD8+, CD4+, NK | 162 |
CD40-L | CD8+ | 168,169 |
GM-CSF + HSV | CD4+, CD8+ | 171 |