Figure 7
From: Effects of statins on the secretion of human serum albumin in cultured HepG2 cells
Effects of simvastatin on HSA mRNA expression in HepG2 cells. HepG2 cells were treated with 0, 1, 5 μM simvastatin for 22 hours. Total RNA was isolated and RT-PCR was subjected. HSA mRNA levels were quantified as described in Methods. Each band density of HSA was normalized by GAPDH and expressed as ratio of HSA mRNA to GAPDH mRNA. Bottom panels are representative of four independent experiments. Bar graph is mean ± SD from these experiments