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Table 3 Scatchard analysis of [3H] QNB binding against atropine in the corpus striatum of Control, Diabetic, and Diabetic+Insulin treated group rats

From: Enhanced muscarinic M1 receptor gene expression in the corpus striatum of streptozotocin-induced diabetic rats

Animal status

Bmax

(fmoles/mg protein)

Kd (nM)

Control

214.00 ± 3.05

0.19 ± 0.01

Diabetic

150.00 ± 5.77***

0.27 ± 0.05***

Diabetic + Insulin treated

184.00 ± 3.05ψψψ

0.17 ± 0.05ψψψ

  1. Values are mean ± S.E.M of 4–6 separate experiments. Each group consist of 6–8 rats
  2. *** P < 0.001 when compared to control, ψψψ P < 0.001 when compared to diabetic group
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Journal of Biomedical Science

ISSN: 1423-0127