Figure 2
From: Investigation on the role of nsSNPs in HNPCC genes – a bioinformatics approach
(A) Native structure of MSH2 gene with 'A' chain of PDB ID 2O8C(orange). (B) Superimposed structure of native tyrosine (orange) with mutant amino acid cysteine (pale green) at 43 position in 2O8C with RMSD 4.30 Å. (C) Superimposed structure of native histidine (orange) with mutant amino acid glutamine (pale green) at 639 position in 2O8C with RMSD 3.93 Å. (D) Superimposed structure of native proline (orange) with mutant amino acid leucine (pale green) at 670 position in 2O8C with RMSD 3.65 Å.