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Table 1 Plasma electrolytes examined in the Munich ENU mouse mutagenesis project

From: N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels

Electrolyte

Intracellular vs. extracellular level

Diagnostic impact

Olympus kit/ISE

Range (mmol/l)a

Ca

Very low

Parathyroidea, bone, kidney

OSR6176

1–4

Cl

Low; major anion in plasma

Osmotic regulation, acid-base status, kidney

Ion-selective electrode

50–200

K

Major cation, low in plasma

K+ transport system, acid-base status, kidney

Ion-selective electrode

1–10

Na

Low; major cation in plasma

Osmotic regulation, kidney

Ion-selective electrode

50–200

P, inorganic

Higher in cells

P uptake, bone, kidney

OSR6122

0.3–6.4

  1. a Linear measurement range (mmol/l) for the Olympus AU400 autoanalyzer (Olympus, Hamburg, Germany) and the reagents for human samples according to the manufacturer.