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Table 2 Amount of thrombosis induced in rats 1, 8, or 24 h following oil smoke exposure (OSE)

From: Substance P scavenger enhances antioxidant defenses and prevents prothrombotic effects on the rat lung after acute exposure to oil smoke

 

Control (n = 8)

OSE (n = 8)

L733060+OSE (n = 8)

Lovastatin+OSE (n = 8)

Vitamin E+OSE (n = 8)

Catechins+OSE (n = 8)

P-value^

Thrombus size (A.U.)

   1 h after OSE

10659 ± 695

45562 ± 3470a

29778 ± 3366a, b

22855 ± 2525b

31712 ± 3751a

26903 ± 2380 a, b

< 0.001*

   8 h after OSE

10509 ± 783

65794 ± 4327a, †

38742 ± 4999a, b

27660 ± 2052a, b

35589 ± 2579a, b

36541 ± 3359a, b

< 0.001*

   24 h after OSE

10458 ± 709

52416 ± 3191a

41574 ± 4772a

36955 ± 4246a, †

49068 ± 4881a, †

38707 ± 5560a

< 0.001*

  1. ^ P-values based on ANOVA test. Pair-wise multiple comparisons between groups determined using Scheffe's test.
  2. * Statistical significance, P < 0.05
  3. a Significantly different from control group at the respective time interval
  4. bSignificantly different from OSE group at the respective time interval
  5. †Significantly different from treatment results at 1 h after OSE