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Table 1 Prediction of cellular localization.

From: Prediction of localization and interactions of apoptotic proteins

Endonuclease G PSORT II (%) WoLF PSORT (%) MultiLoc (%) Cello (reliability)
mitochondrion 30.4 25.9 98.0 3.08
cytoplasm 34.8 6.9 0.0 0.33
endoplasmic reticulum 8.7 - - 0.03
Golgi apparatus - 10.3 - 0.01
lysosome/vacuole 8.7 13.8 - 0.03
peroxisome - 15.5 1.0 0.20
plasma membrane 8.7 - - 0.40
nucleus 8.7 3.4 - 0.43
cystoskeleton - - - 0.01
AIF     
mitochondrion 39.1 69.0 97.0 2.53
cytoplasm 26.1 8.6 1.0 0.40
endoplasmic reticulum 17.4 - - 0.01
Golgi apparatus 13.0 - - 0.02
lysosome/vacuole 4.3 - - 0.01
peroxisome - 6.9 2.0 0.14
plasma membrane - 6.9 - 0.04
nucleus - 5.2 - 0.04
cystoskeleton - - - 0.00
AMID     
mitochondrion 8.7 3.1 7.0 1.58
cytoplasm 60.9 12.5 59.0 0.58
endoplasmic reticulum - - - 0.05
Golgi apparatus 13.0 3.1 - 0.04
lysosome/vacuole 4.3 - - 0.03
peroxisome - 12.5 31.0 0.25
plasma membrane - 18.8 - 0.37
nucleus 4.3 12.5 - 0.17
cystoskeleton - - - 0.01
Cyclophilin A     
mitochondrion 4.3 6.3 1.0 0.33
cytoplasm 60.9 79.7 93.0 4.18
endoplasmic reticulum - - - 0.09
Golgi apparatus - 3.2 - 0.01
lysosome/vacuole 4.3 - - 0.02
peroxisome - - 5.0 0.03
plasma membrane - - - 0.03
nucleus 17.4 2.5 - 0.12
cytoskeleton 4.3 - - 0.00
HSP70-1     
mitochondrion - 3.2 2.0 0.47
cytoplasm 73.9 59.4 36.0 3.08
endoplasmic reticulum 4.3 - - 0.22
Golgi apparatus - - - 0.04
lysosome/vacuole - - - 0.01
peroxisome - - 61.0 0.10
plasma membrane - 3.2 - 0.02
nucleus 21.7 21.9 - 0.20
cytoskeleton - 9.4 - 0.02
DNA topoisomerase II α     
mitochondrion - 1.6 - 0.10
cytoplasm 17.4 31.3 2.0 0.30
endoplasmic reticulum - - - 0.03
Golgi apparatus - - - 0.01
lysosome/vacuole - - - 0.00
peroxisome - - 1.0 0.01
plasma membrane - - - 0.11
nucleus 78.3 67.5 96.0 4.33
cytoskeleton - - - 0.02
  1. Sequence analysis of localization of endonuclease G, AIF, AMID, cyclophilin A, HSP70-1, and DNA topoisomerase II α. Bold underlined numbers represent final combined prediction result for corresponding protein. Italic underlined numbers mark the highest probabilities, which are different from the final combined prediction result.