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Table 1 Prediction of cellular localization.

From: Prediction of localization and interactions of apoptotic proteins

Endonuclease G

PSORT II (%)

WoLF PSORT (%)

MultiLoc (%)

Cello (reliability)

mitochondrion

30.4

25.9

98.0

3.08

cytoplasm

34.8

6.9

0.0

0.33

endoplasmic reticulum

8.7

-

-

0.03

Golgi apparatus

-

10.3

-

0.01

lysosome/vacuole

8.7

13.8

-

0.03

peroxisome

-

15.5

1.0

0.20

plasma membrane

8.7

-

-

0.40

nucleus

8.7

3.4

-

0.43

cystoskeleton

-

-

-

0.01

AIF

    

mitochondrion

39.1

69.0

97.0

2.53

cytoplasm

26.1

8.6

1.0

0.40

endoplasmic reticulum

17.4

-

-

0.01

Golgi apparatus

13.0

-

-

0.02

lysosome/vacuole

4.3

-

-

0.01

peroxisome

-

6.9

2.0

0.14

plasma membrane

-

6.9

-

0.04

nucleus

-

5.2

-

0.04

cystoskeleton

-

-

-

0.00

AMID

    

mitochondrion

8.7

3.1

7.0

1.58

cytoplasm

60.9

12.5

59.0

0.58

endoplasmic reticulum

-

-

-

0.05

Golgi apparatus

13.0

3.1

-

0.04

lysosome/vacuole

4.3

-

-

0.03

peroxisome

-

12.5

31.0

0.25

plasma membrane

-

18.8

-

0.37

nucleus

4.3

12.5

-

0.17

cystoskeleton

-

-

-

0.01

Cyclophilin A

    

mitochondrion

4.3

6.3

1.0

0.33

cytoplasm

60.9

79.7

93.0

4.18

endoplasmic reticulum

-

-

-

0.09

Golgi apparatus

-

3.2

-

0.01

lysosome/vacuole

4.3

-

-

0.02

peroxisome

-

-

5.0

0.03

plasma membrane

-

-

-

0.03

nucleus

17.4

2.5

-

0.12

cytoskeleton

4.3

-

-

0.00

HSP70-1

    

mitochondrion

-

3.2

2.0

0.47

cytoplasm

73.9

59.4

36.0

3.08

endoplasmic reticulum

4.3

-

-

0.22

Golgi apparatus

-

-

-

0.04

lysosome/vacuole

-

-

-

0.01

peroxisome

-

-

61.0

0.10

plasma membrane

-

3.2

-

0.02

nucleus

21.7

21.9

-

0.20

cytoskeleton

-

9.4

-

0.02

DNA topoisomerase II α

    

mitochondrion

-

1.6

-

0.10

cytoplasm

17.4

31.3

2.0

0.30

endoplasmic reticulum

-

-

-

0.03

Golgi apparatus

-

-

-

0.01

lysosome/vacuole

-

-

-

0.00

peroxisome

-

-

1.0

0.01

plasma membrane

-

-

-

0.11

nucleus

78.3

67.5

96.0

4.33

cytoskeleton

-

-

-

0.02

  1. Sequence analysis of localization of endonuclease G, AIF, AMID, cyclophilin A, HSP70-1, and DNA topoisomerase II α. Bold underlined numbers represent final combined prediction result for corresponding protein. Italic underlined numbers mark the highest probabilities, which are different from the final combined prediction result.