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Figure 1 | Journal of Biomedical Science

Figure 1

From: Activation of estrogen receptor β-dependent nitric oxide signaling mediates the hypotensive effects of estrogen in the rostral ventrolateral medulla of anesthetized rats

Figure 1

Cardiovascular effects after microinjection bilaterally into the RVLM of E2β. Time-course of the changes in mean systemic arterial pressure (MSAP), heart rate (HR) and total power density of vasomotor components (0–0.8 Hz) of systemic arterial pressure (SAP) spectrum in anaesthetized rats that received microinjection bilaterally into the rostral ventrolateral medulla (RVLM, at time 0) of artificial cerebrospinal fluid (aCSF), 17β-estradiol (E2β, 0.5, 1 or 5 pmol), or 17α-estradiol (E2α, 5 pmol). Values are presented as mean ± S.E.M., n = 6–8 animals per experimental group. *P < 0.05 versus corresponding aCSF group in the Scheffé multiple range test.

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