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Figure 2 | Journal of Biomedical Science

Figure 2

From: Activation of estrogen receptor β-dependent nitric oxide signaling mediates the hypotensive effects of estrogen in the rostral ventrolateral medulla of anesthetized rats

Figure 2

Effects of ER antagonist on the E2β-induced cardiovascular depressive responses. Time-course of the changes in MSAP and total power density of vasomotor components (0–0.8 Hz) of SAP spectrum in anaesthetized rats that received microinjection bilaterally into the RVLM (at time 0) of aCSF, or E2β (1 pmol) given together with ICI 182780 (ICI, 0.25 or 0.5 pmol) or 5% DMSO. Values are presented as mean ± S.E.M., n = 6–8 animals per experimental group. *P < 0.05 versus corresponding aCSF group, and #P < 0.05 versus corresponding E2β+DMSO group in the Scheffé multiple range test.

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