Skip to main content
Figure 4 | Journal of Biomedical Science

Figure 4

From: Activation of estrogen receptor β-dependent nitric oxide signaling mediates the hypotensive effects of estrogen in the rostral ventrolateral medulla of anesthetized rats

Figure 4

Effects of NOS inhibitor on the ERβ agonist-induced cardiovascular depressive effects. Time-course of the changes in MSAP and total power density of vasomotor components (0–0.8 Hz) of SAP spectrum in anaesthetized rats that received microinjection bilaterally into the RVLM (at time 0) of aCSF, 3% methanol (MeOH), or DPN (2 pmol) given together with L-NAME (5 nmol), SMT (25 pmol), 7-NI (0.5 pmol), L-NIO (2.5 pmol) or 3% MeOH. Values are mean ± S.E.M., n = 6–7 animals per experimental group. *P < 0.05 versus corresponding MeOH group, and #P < 0.05 versus corresponding DPN+MeOH group in the Scheffé multiple range test. Data on aCSF are not shown because they in essence duplicated those by 3% MeOH.

Back to article page