Figure 1

Body weight (BW), plasma cholesterol, and plasma triglyceride levels in p21^-/- and wild type control mice. A: Differential effect of high fat diet on weight gain in wild type mice (n = 8) and p21^-/- (n = 8) mice is shown. Values are means ± SEM, Weight gain in p21^-/- mice fed with high fat diet is compared to p21^-/- mice fed with regular diet and wild type mice fed with high fat diet. B: Differential effect on the effect of high fat diet on plasma levels of cholesterol (open bars) and triglycerides (closed bars) in p21^-/- and wild type mice fed with high fat and regular diet is shown.