Figure 3

Quantitative mRNA expression of IFN-γ, PPAR-γ and NADPH oxidase components (p22^phox, NOX-1 and Rac-1) in aortic tissues from p21^-/- mice. Amplification curves for IFN-g in RNA isolated from aorta from mice fed with high fat diet (HFD) and regular diet (RGD) are shown. Significantly higher Relative fold expression of IFN-γ (B), PPAR-γ (B) mRNA is shown in Wild type (open bars) and p21^-/- mice (closed bars). The values are means ± SEM of fold increase in high fat diet compared to the results obtained from mice fed with regular diet.