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Figure 1 | Journal of Biomedical Science

Figure 1

From: Impairment of insulin-stimulated Akt/GLUT4 signaling is associated with cardiac contractile dysfunction and aggravates I/R injury in STZ-diabetic Rats

Figure 1

The effects of diabetes on I/R-induced ventricular rhythm disturbances including VPC (A), VT (B), and VF (C) were determined during ischemic period (1 h) in the age-matched controlled (n = 7), STZ-diabetic (n = 28), and insulin-treated diabetic (n = 9) rats. Data were expressed as means ± SEM, # P < 0.05 vs. DM. C, age-matched control; CS, control sham; DM, STZ-induced diabetes; DMS, DM sham; DMI, diabetes treated with insulin (4 IU/day for 5 days); DMIS, DMI sham; I/R, myocardial ischemia 1 h following by a 3 h of reperfusion; VPC, ventricular premature complexes; VT, ventricular tachycardia; VF, ventricular fibrillation.

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