From: Inhibitory effects of armepavine against hepatic fibrosis in rats
Group | SO + | BDL + | BDL + sil | BDL + Arm | BDL + Arm |
---|---|---|---|---|---|
 | vehicle | vehicle | (50 mg/kg) | (3 mg/kg) | (10 mg/kg) |
col1α2/GAPDH | 1.00 ± 0.44 | 12.5 ± 0.2* | 7.31 ± 0.11*,# | 7.45 ± 0.08*,# | 5.09 ± 0.23*,# |
TGF-β1/GAPDH | 1.00 ± 0.81 | 21.5 ± 0.2* | 13.1 ± 0.9*,# | 14.5 ± 0.8*,# | 7.09 ± 1.72*,# |
TIMP-1/GAPDH | 1.01 ± 0.84 | 28.0 ± 2.6* | 4.93 ± 1.88*,# | 4.36 ± 1.70*,# | 3.87 ± 1.59*,# |
ICAM-1/GAPDH | 1.00 ± 0.20 | 22.5 ± 0.5* | 12.2 ± 0.1*,# | 15.5 ± 0.2*,# | 7.03 ± 0.35*,# |
iNOS/GAPDH | 1.00 ± 0.08 | 7.53 ± 0.17* | 5.31 ± 0.09*,# | 6.45 ± 0.08*,# | 3.09 ± 0.31*,# |
IL-6/GAPDH | 1.00 ± 0.10 | 31.5 ± 0.3* | 11.3 ± 0.1*,# | 10.5 ± 0.1*,# | 4.09 ± 0.17*,# |
Metallothionein/GAPDH | 1.00 ± 0.10 | 0.34 ± 0.06* | 0.56 ± 0.08*,# | 0.37 ± 0.10* | 0.57 ± 0.05*,# |