Figure 3
From: Damaged DNA-binding protein 2 (DDB2) protects against UV irradiation in human cells and Drosophila
Stimulation of cFLIP expression and attenuation of UV sensitivity by forced expression of DDB2. (A) Overexpression of cFLIP in HR3 cells. The plotted values represent means ± S.D. of three experiments (right panel). (B) Stimulation of cFLIP expression by forced expression of DDB2. Whole cell extracts of HR18 cells, treated as indicated, were subjected to immunoblot analysis with specific antibodies. (C) Cell sensitivity to UV after Ad-DDB2 virus infection. The plotted values represent means ± S.D. of three experiments. ** Significant difference against control (p < 0.05).