17-AAG suppresses RPE cells proliferation. ARPE-19 cells were treated with various concentrations of 17-AAG for 24, 48, or 72 h. Their viability was evaluated using the MTT assay, as described in the Methods section. Values are presented as means ± SD for triplicate cultures of each cell and are presented as the percentage of control cells that received medium only. 17-AAG reduces the viability of ARPE-19 cells in a dose-dependent manner (p < 0.05). No time-dependent decrease in viability occurs, regardless of the concentration of 17-AAG (p > 0.05). *, p < 0.05.