Figure 2
From: Molecular oncology focus - Is carcinogenesis a 'mitochondriopathy'?
Possible usage of mitochondrial bio-markers in cancer screening, diagnostics and prognosis. The co-dependence of mitochondrial failure (orange) and cancer development (red); mitochondrial disruption is accompanied by cell transformation and cancer development (red/orange-blue dashed area). At each stage of tumor growth, mitochondrial markers (purple, pink, yellow) may be used, and provide new tools of clinical utility, hence uniting molecular biology (green) and clinical diagnostics (blue) in 'mitochondrial oncology' (blue-green dashed area).