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Table 3 Mutation analysis of the EGFR gene by multiplex PCR and primer extension.

From: Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer

NSCLC subtype

Case(s) with EGFR mutation(s)

 

E746-A750 del

L747-S752 del

L858R

-216 G/T

2235-2249 del

2236-2250 del

2240-2257 del

2573 T>G

Adenocarcinoma (n = 26)

3

1

3

0

8

Bronchioloalveolar carcinoma (n = 6)

1

2

0

0

1

Squamous cell carcinoma (n = 33)

3

0

0

0

2

Adenosquamous carcinoma (n = 5)

0

0

0

1

0

Others (n = 11)

0

0

0

0

1

Total (n = 81)

7

3

3

1

12