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Figure 3 | Journal of Biomedical Science

Figure 3

From: Caffeine and a selective adenosine A2A receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice

Figure 3

Effect of chronic caffeine and SCH58261 administration on the striatal amines (n = 3-4). a DA leves in the striatum after chronic caffeine treatment was increased. Data represent means ± SEM. P < 0.01 versus saline-treated group (by Student's test). b, c Increase in DOPAC and HVA levels were also noted but were not statistically significant. d DA level in the striatum after chronic SCH58261 treatment was increased. Data represent means ± SEM. P < 0.01 versus DMSO-treated group (by Student's test). e, f Increase in DOPAC and HVA levels were also noted. P < 0.001 and P < 0.05 versus DMSO-treated group respectively (by Student's test).

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