Figure 4

Representative Western immunoblots of phsopho-S31-TH (a, c) and total TH (b, d)in the striatum of the chronic saline- or caffeine-treated groups and chronic DMSO- or SCH58261-treated groups 30 min after a challenge with caffeine (10 mg/kg) or SCH58261 (2 mg/kg). The experiment was repeated at least three times. The bar graphs indicate quantitative count of phospho-Ser31-TH and total TH, normalized with actin signals (n = 3-6; *P < 0.05 and **P < 0.01 by Student's test).