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Figure 5 | Journal of Biomedical Science

Figure 5

From: Commensal microflora induce host defense and decrease bacterial translocation in burn mice through toll-like receptor 4

Figure 5

Oral TLR4 ligand supplement after burn decreased bacterial translocation (BT) and increased bacterial killing activity of macrophages as well as TLR4 expression of intestinal mucosa. (A) Oral antibiotics feeding after burn (Burn+Anti) increased BT to MLN in comparison to burn group and LPS supplement reversed it. * p < 0.05, vs. burn group. # p < 0.05, vs. burn + antibiotics group. (B) Oral antibiotics feeding after burn induced a significant increase of bacterial retention in both peritoneal macrophages and bone marrow cells. LPS supplement (Burn+Anti+LPS) decreased bacterial retention of peritoneal macrophages and bone marrow cells in comparison with antibiotics + burn group (Burn + Anti). * p < 0.05, vs. burn group. # p < 0.05, vs. antibiotics + burn group. (C) Oral antibiotics feeding after burn decreased TLR4 mRNA expression of intestinal mucosa in comparison with burn group and LPS supplement increased it. * p < 0.05, vs. burn group. # p < 0.05, vs. burn + antibiotics group

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Journal of Biomedical Science

ISSN: 1423-0127