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Table 1 Effect of α-Tocopherol treatment in ischemic reperfusion injury model in rats for 6 weeks on Motor function, Sensory response and Placing/Stepping reflex scores

From: A potential protective effect of α-tocopherol on vascular complication in spinal cord reperfusion injury in rats

 

Test

C

CE

S

IRI

IRIE

p-value

Motor assessment

Mean ± SD

4.8 ± 0.4(a)

4.8 ± 0.4(a)

4.0 ± 1.1(a)

1.2 ± 1.0(b)

3.8 ± 1.0(a)

<0.001

Sensory assessment

Normal

8

9

7

2

7

 
  

(80%)(a)

(90%)(a)

(70%)(a)

(20%)(b)

(70%)(a)

 
 

Affected

2

1

3

8

3

<0.05

  

(20%)(a)

(10%)(a)

(30%)(a)

(80%)(b)

(30%)(a)

 

Placing/Stepping reflex

Normal

8

9

7

2

8

 
  

(80%)(a)

(90%)(a)

(70%)(a)

(20%)(b)

(80%)(a)

 
 

Impaired

2

1

3

2

1

<0.01

  

(20%)(a)

(10%)(a)

(30%)(a)

(20%)(a)

(10%)(a)

 
 

Lost

0

0

0

6

1

 
  

(0%)(a)

(0%)(a)

(0%)(a)

(60%)(b)

(10%)(a)

 
  1. C: Control group; CE: α-Tocopherol control group; S: Sham group; IRI: Ischemic Reperfusion Injury group; IRIE: α-Tocopherol-treated ischemic reperfusion injury group. Results are expressed as mean ± SD (n = 10).
  2. P value < 0.05 is considered significant.
  3. Groups with different letters are statistically significant (p < 0.001)