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Table 2 Scatchard analysis of [3H] QNB binding against pirenzepine in the cerebellum of Control, Diabetic, Diabetic + IIH and Control + IIH Group of rats

From: Hypoglycemia induced changes in cholinergic receptor expression in the cerebellum of diabetic rats

Experimental Group Bmax
(fmoles/mg protein)
Kd
(nM)
Control 127 ± 12.4 0.40 ± 0.03
Diabetic 183 ± 11.5 a 0.41 ± 0.02
D + IIH 245 ± 10.5 ab 0.50 ± 0.03d
C + IIH 296 ± 9.8 abc 0.54 ± 0.02d
  1. Values are Mean ± S.E.M. of 4-6 separate experiments. Each group consists of 6-8 rats. a p < 0.001 when compared to control, b p < 0.001 when compared to Diabetic, c p < 0.01 when compared to D + IIH, d p < 0.01 when compared to diabetic. IIH- Insulin Induced Hypoglycemia.
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