Figure 6

Knockdown of ho-1 gene antagonized selectively the activation of HO-1 in RVLM. Illustrative gels or summary of fold changes against aCSF controls in ratio of HO-1 (A) or HO-2 (B) relative to β-actin protein detected in ventrolateral medulla of rats that received knockdown of ho-1 or ho-2 gene in RVLM 24 h before induction of Mev intoxication. Values are mean ± SEM of triplicate analyses on samples pooled from 4-6 animals per experimental group. *P < 0.05 versus aCSF group and ⁺P < 0.05 versus Mev group in the Scheffé multiple-range test. Note that dividing lines are placed on the gel images to denote groupings of images from different parts of the same gel.