Table 8 Polymorphisms found in the coding region of mtDNA of VSCC patients.
From: Mitochondrial genotype in vulvar carcinoma - cuckoo in the nest
mtDNA position (rCRS) | Polymorphism | Case No | No | A/G/C/T/del frequency mtDB | P-value | Region/population where sequence variant predominantly found |
|---|---|---|---|---|---|---|
709 12 S rRNA | G > A | 17,25,26,29,33, 41,42,46 | 8 | 444/2260/0 | 0.053 | Africa, native Americans, Japan, American, Finland, Italy, India |
750 12 S rRNA | A > G | 13,15,16,17,18,22,25,26,27,28,29,30,33,34,38,39,40,41,42,44,45,46,49,50,51 | 25 | 22/2682/0/0 | 1.000 | CRS is a rare variant; G is very common in the whole world, A/G is consensus mutation |