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Table 1 Genotype and allele frequencies of phospholipase A2 receptor 1 (PLA2R1) single nucleotide polymorphisms (SNPs) in patients with idiopathic membranous nephropathy (IMN) vs healthy controls

From: Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan

SNPs Controls
N (%)
IMN
N (%)
p-Valuea Odds ratio (95% CI)b
Alleles
rs6757188     
C allele 76 (35.8) 83 (32.3) 0.402 1
T allele 136 (64.2) 175 (67.8)   1.178 (0.803-1.729)
Total 212 (100) 258 (100)   
rs35771982     
C allele 56 (26.4) 41 (15.9) 0.005 1
G allele 156 (73.6) 217 (84.1)   1.900 (1.209-2.987)
Total 212 (100) 258 (100)   
Genotypes
rs6757188     
C/C 9 (8.5) 15 (11.6) 0.113 1
C/T 58 (54.7) 53 (41.1)   0.548 (0.221-1.357)
T/T 39 (36.8) 61 (47.3)   0.938 (0.374-2.352)
Total 106 (100) 129 (100)   
rs35771982     
C/C 8 (7.5) 2 (1.6) 0.015 1
C/G 40 (37.7) 37 (28.7)   3.700 (0.738-18.560)
G/G 58 (54.7) 90 (69.7)   6.207 (1.273-30.262)
Total 106 (100) 129 (100)   
  1. Abbreviation: CI, confidence interval.
  2. a Genotype frequencies were determined by χ2 test using 2 × 3 contingency tables between patients with IMN and healthy controls. Allele frequencies and restricted genotypes were determined by χ2 test using 2 × 2 contingency tables between patients with IMN and healthy controls.
  3. b Odds ratios and 95% CI per genotype and allele were estimated by applying unconditional logistic regression between patients with IMN and healthy controls.