Figure 4

GTH modulates the activity of matrix metalloproteinase. RAW264.7 cells were incubated with different concentrations of GTH for 24 hrs, followed by stimulation with LPS. The activity of (A) MMP-9 and (B) MMP-2 was analyzed by gelatin zymography after 12-hr LPS stimulation. Values represent mean ± SEM (n = 3, ** = P < 0.001 compared with LPS alone).