Figure 1

Latency to seizures Two-month-old male mice treated with 5 mg kg^-1 picrotoxin presented with short latency periods (control) that were also of short duration. Seizures were nearly always fatal (66%). Treatment with taurine significantly increased latency and duration, whether route of administration was injection 15 min prior to picrotoxin injection (Tau-Inj) or chronic feeding of taurine (Tau-Fed). In both cases, taurine significantly improved survivability (P<0.05).