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Figure 2 | Journal of Biomedical Science

Figure 2

From: Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity

Figure 2

Transient expression of siRNA against HSPA4 or HSPA14 in H1299 cells decreased the in vitro migration and invasion activity. (A) & (C) Transient transfections of pSUPER-HSPA4i or pSUPER-HSPA14i decreased the expression of endogenous HSPA4 or HSPA14 in H1299 cells. (B) & (D) A significant decrease in migration and invasion activity in H1299 cells was shown by transient transfections of pSUPER-HSPA4i or pSUPER-HSPA14i vector into H1299 cells. The asterisk (*) indicated statistical significance (P < 0.05) between pSUPER vector control transfections vs. pSUPER-HSPA4i or pSUPER-HSPA14i transfections.

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Journal of Biomedical Science

ISSN: 1423-0127