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Figure 3 | Journal of Biomedical Science

Figure 3

From: Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity

Figure 3

H1299NBS1 stable clones expressing siRNA against HSPA4 or HSPA14 decreased the in vitro migration and invasion activity. (A) & (C) H1299NBS1 clones stably transfected with pSUPER-HSPA4i or pSUPER-HSPA14i vector showed the decreased expression of endogenous HSPA4 or HSPA14 in H1299NBS1 cells. (B) & (D) A significant decrease in migration and invasion activity was shown in H1299NBS1 cells receiving siRNA against HSPA4 or HSPA14. The asterisk (*) indicated statistical significance (p < 0.05) between H1299NBS1 clones expressing siRNA and H1299NBS1 control clones.

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