Figure 7From: Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injuryImprovement of hindlimb locomotor recovery in SCI rats by treatment with chABC. (A). Rats received administration with vehicle (n = 4), or with chABC (0.03 U/injection, 0.06 U/rat) immediately after SCI (n = 4) or at 3 day post SCI (n = 4). To examine hindlimb locomotor function in SCI rats, the BBB open-field analysis was conducted. Data are presented as mean ± SEM. *p <0.05 versus the vehicle-treated group. (B). The spinal cord tissues were collected from SCI rats at day 31. The longitudinal tissue sections containing the LC were subjected to immunofluorescence for GAP-43. Arrowheads indicate the fine fragmented GAP-43-positive neuronal fibers in the vehicle-treated control. Arrows and open arrows show the GAP-43-positive neuronal bundles in chABC-treated group. Scale bar, 100 μm (left panel) and 50 μm (middle and right panels).Back to article page