Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury

Table 1 List of proteins that were down-regulated in the lesion center at day 14 after SCI compared to 1 day after SCI.

Spot no.	Function	Protein name	Protein ID	Expression (14d/1d)	14d_mean (SEM)	1d_mean (SEM)	p value	Mw/pI	Score
1~3	acute-phase response	Serotransferrin	TRFE	down	1.241 (0.394)	3.097 (0.627)	0.035	78512/7.14	186
121	chaperone	Stress-70 protein, mitochondrial	GRP75	down	0.109 (0.032)	0.608 (0.132)	0.008	74097/5.97	64
102	metabolism	Carbonic anhydrase 1	CAH1	down	ND	0.212 (0.084)	NA	28282/6.86	68
41, 42, 97	metabolism	Fructose-bisphosphate aldolase C	ALDOC	down	0.440 (0.047)	1.283 (0.263)	0.009	39658/6.67	187
96	oxidoreduction	Sorbitol dehydrogenase	DHSO	down	ND	0.079 (0.056)	NA	38780/7.14	66
77	stress response	Heat shock 70 kDa protein 4	HSP74	down	ND	0.193 (0.087)	NA	93997/5.13	127
78	transport	Hemopexin	HEMO	down	0.360 (0.142)	0.997 (0.123)	0.023	52060/7.58	139

The proteins changed at least 1.5-fold were listed above. The proteins were downregulated with a p value < 0.05. NA, not applicable; ND, non-detectable.

ISSN: 1423-0127