Skip to main content

Advertisement

Table 3 List of proteins that showed a decreased (down) or an increased (up) trend (p > 0.05) in the lesion center of the injured spinal cord from the subacute (day 14) SCI group when compared to that detected in the acute (day 1) SCI group.

From: Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury

Spot
no.
Function Protein name Protein ID Expression
(14d/1d)
14d_mean
(SEM)
1d_mean
(SEM)
p value Mw/pI Score  
119 actin filament binding Fascin FSCN1 down 0.053
(0.022)
0.106
(0.046)
0.406 54474/6.44 184  
6,7 anti-apoptosis 60 kDa heat shock protein, mitochondrial CH60 down 0.123
(0.050)
0.744
(0.340)
0.052 61088/5.91 96  
11,12 isomerase Protein disulfide-isomerase A3, p58 PDIA3 down 0.618
(0.188)
1.386
(0.955)
0.344 57044/5.88 80  
13,14 metabolism D-3-phosphoglycerate dehydrogenase SERA down 0.096
(0.081)
0.231
(0.087)
0.355 56457/6.28 90  
38 metabolism Acetyl-CoA acetyltransferase, cytosolic THIC down 0.052
(0.009)
0.189
(0.112)
0.272 41538/6.86 60  
44,45 metabolism Fructose-bisphosphate aldolase A ALDOA down 1.256
(0.239)
1.905
(0.570)
0.292 39783/8.31 125  
46 metabolism L-lactate dehydrogenase B chain LDHB down 0.396
(0.072)
1.092
(0.613)
0.283 36874/5.70 71  
99 metabolism Malate dehydrogenase, cytoplasmic MDHC down 0.240
(0.087)
0.648
(0.238)
0.121 36117/8.93 217  
100, 101 metabolism Carbonic anhydrase 2 CAH2 down 0.053
(0.025)
0.484
(0.228)
0.071 29096/6.89 76  
109 metabolism Glycine amidinotransferase, mitochondrial GATM down 0.032
(0.011)
0.052
(0.016)
0.416 48724/7.17 146  
113~ 115 metabolism Aconitate hydratase, mitochondrial ACON down 0.164
(0.058)
0.712
(0.323)
0.102 86121/7.87 183  
39 metabolism Creatine kinase M-type KCRM down 0.066
(0.020)
0.101
(0.032)
0.391 43246/6.58 63  
30,31 metabolism Phosphoglycerate kinase 1 PGK1 down 0.452
(0.123)
0.803
(0.468)
0.446 44909/8.02 116  
9,10 microtubule Tubulin alpha-1B chain TBA1B down 1.111
(0.488)
1.941
(0.876)
0.370 50120/4.94 86  
89 microtubule Tubulin alpha-1A chain TBA1A down 0.146
(0.039)
0.279
(0.062)
0.102 50788/4.94 135  
88,90, 91 neurogenesis Dihydropyrimidinase-related protein 2 DPYL2 down 0.176
(0.088)
0.313
(0.116)
0.366 62638/5.95 105  
92~94 neuron differentiation Dihydropyrimidinase-related protein 5 DPYL5 down 0.061
(0.046)
0.319
(0.189)
0.132 61501/6.60 117  
105 oxidoreduction Dihydrolipoyl dehydrogenase, mitochondrial DLDH down 0.151
(0.069)
0.376
(0.165)
0.214 54574/7.96 84  
95 oxidoreduction Catalase CATA down 0.028
(0.027)
0.056
(0.013)
0.364 59719/7.07 187  
82,83 protease inhibitor Serine protease inhibitor A3K SPA3K down 0.299
(0.078)
0.866
(0.289)
0.073 46532/5.31 113  
15 protein assembly Stress-induced-phosphoprotein 1, Hsc70/Hsp90-organizing protein STIP1 down 0.035
(0.020)
0.172
(0.139)
0.288 63158/6.40 65  
17 proteolysis Cytosol aminopeptidase AMPL down 0.122
(0.040)
0.188
(0.064)
0.400 56514/6.77 62  
120 stress response Heat shock cognate 71 kDa protein HSP7C down 0.391
(0.257)
0.865
(0.332)
0.288 71055/5.37 123  
119 actin filament binding Fascin FSCN1 down 0.053
(0.022)
0.106
(0.046)
0.406 54474/6.44 184  
63 anti-apoptosis Lactoylglutathione lyase LGUL up 0.488
(0.078)
0.231
(0.090)
0.074 20977/5.12 67  
62 cell proliferation Translationally-controlled tumor protein TCTP up 0.181
(0.051)
0.058
(0.057)
0.216 19564/4.76 128  
8 chaperone Protein disulfide-isomerase PDIA1 up 0.897
(0.253)
0.263
(0.099)
0.097 57315/4.82 197  
67 chaperone Protein DJ-1 PARK7 up 0.260
(0.087)
0.113
(0.034)
0.198 19961/6.32 68  
124 chaperone T-complex protein 1 subunit beta TCPB up 0.078
(0.015)
0.031
(0.030)
0.190 57422/6.01 76  
21 metabolism Elongation factor 1-alpha 1 EF1A1 up 0.631
(0.273)
0.160
(0.055)
0.142 50424/9.10 77  
29 metabolism Isocitrate dehydrogenase [NADP] IDHC up 0.113
(0.111)
0.056
(0.044)
0.679 47047/6.53 108  
50 metabolism L-lactate dehydrogenase A chain LDHA up 0.209
(0.045)
0.080
(0.028)
0.058 36712/8.45 64  
53 metabolism Dimethylarginine dimethylaminohydrolase 2 DDAH2 up 0.118
(0.044)
0.015
(0.014)
0.158 30011/5.66 116  
73,75 oxidoreduction Peroxiredoxin-1 PRDX1 up 0.684
(0.378)
0.076
(0.036)
0.158 22323/8.27 91  
65 oxidoreduction Peroxiredoxin-6 PRDX6 up 0.199
(0.104)
0.074
(0.023)
0.359 24860/5.64 74  
79 protein assembly 78 kDa glucose-regulated protein GRP78 up 0.323
(0.116)
0.136
(0.045)
0.245 72473/5.07 285  
51 proteolysis Cathepsin B CATB up 0.245
(0.081)
0.159
(0,158)
0.619 38358/5.36 72  
106, 107 proteolysis Cathepsin D CATD up 0.840
(0.373)
0.036
(0.026)
0.075 45165/6.66 132  
64 signal transduction Phosphatidylethanolamine-binding protein 1 PEBP1 up 1.539
(0.440)
0.910
(0.214)
0.277 20902/5.48 82  
72 signal transduction GTP-binding nuclear protein Ran RAN up 0.184
(0.090)
0.116
(0.055)
0.606 46532/5.31 113  
57 stress response Endoplasmic reticulum protein ERp29 ERP29 up 0.118
(0.091)
0.029
(0.029)
0.513 28614/6.23 63  
56 ubiquitin-dependent protein catabolism Proteasome subunit alpha type-1 PSA1 up 0.177
(0.038)
0.091
(0.027)
0.162 29784/6.15 64