Table 4 List of proteins that were changed less than 1.5-fold in the lesion center of the injured spinal cord from the subacute (day 14) SCI group when compared to that detected in the acute (day 1) SCI group.

128

actin binding

WD repeat-containing protein 1

WDR1

0.036

(0.035)

0.034

(0.017)

0.980

66824/6.15

76

80

acute phase

T-kininogen 2

KNT2

0.648

(0.352)

0.950

(0.085)

0.481

48757/5.94

102

81

acute phase

T-kininogen 1

KNT1

0.270

(0.040)

0.202

(0.055)

0.353

48828/6.08

144

87

cytoskeleton

Glial fibrillary acidic protein

GFAP

0.458

(0.093)

0.535

(0.036)

0.469

49927/5.35

144

16

metabolism

Bifunctional purine biosynthesis protein PURH

PUR9

0.039

(0.009)

0.056

(0.055)

0.629

64681/6.69

70

18~20

metabolism

Pyruvate kinase isozymes M1/M2

KPYM

0.719

(0.280)

0.864

(0.433)

0.778

58294/6.63

134

24

metabolism

Gamma-enolase

ENOG

0.343

(0.130)

0.446

(0.114)

0.581

47111/5.03

155

25

metabolism

Creatine kinase B-type

KCRB

0.996

(0.226)

0.767

(0.177)

0.469

42983/5.30

151

26~28

metabolism

Alpha-enolase

ENOA

0.714

(0.271)

1.040

(0.364)

0.486

47440/6.16

185

32

metabolism

3-ketoacyl-CoA thiolase, mitochondrial

THIM

0.133

(0.040)

0.153

(0.061)

0.782

42244/8.09

137

36,37

metabolism

Glutamine synthetase

GLNA

0.338

(0.096)

0.249

(0.080)

0.505

42982/6.64

179

47~49

metabolism

Glyceraldehyde-3-phosphate dehydrogenase GAPDH

G3P

2.351

(0.603)

3.215

(1.492)

0.577

36090/8.14

88

68,70, 71

metabolism

Triosephosphate isomerase

TPIS

0.609

(0.219)

0.413

(0.134)

0.461

27345/6.89

164

36,37

metabolism

Glutamine synthetase

GLNA

0.338

(0.096)

0.249

(0.080)

0.505

42982/6.64

179

111

metabolism

Malate dehydrogenase, mitochondrial

MDHM

0.874

(0.241)

0.726

(0.240)

0.682

36117/8.93

217

123

metabolism

Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

ODPB

0.103

(0.059)

0.070

(0.002)

0.636

38957/6.20

100

125, 126

metabolism

Transketolase

TKT

0.143

(0.047)

0.147

(0.081)

0.970

67601/7.23

92

103

microtubule

Tubulin alpha-1C chain

TBA1C

0.132

(0.049)

0.098

(0.021)

0.559

49905/4.96

64

112

microtubule

Tubulin beta-2C chain

TBB2C

1.464

(0.416)

1.289

(0.343)

0.764

50225/4.79

210

43

oxidoreduction

Alcohol dehydrogenase [NADP+]

AK1A1

0.153

(0.030)

0.135

(0.105)

0.860

36711/6.84

84

98

oxidoreduction

Aldose reductase

ALDR

0.128

(0.047)

0.124

(0.042)

0.956

35774/6.26

101

116~ 118

oxidoreduction

Glutamate dehydrogenase 1, mitochondrial

DHE3

0.286

(0.100)

0.410

(0.233)

0.613

61719/8.05

172

86

protease inhibitor

Serine protease inhibitor A3N

SPA3N

0.751

(0.144)

0.748

(0.369)

0.995

46622/5.33

109

23

proteolysis

Cytosolic non-specific dipeptidase

CNDP2

0.174

(0.029)

0.176

(0.083)

0.983

53116/5.43

120

34

proteolysis

Aminoacylase-1A

ACY1A

0.058

(0.014)

0.074

(0.031)

0.628

46060/6.03

77

104

secreted glycoprotein

Alpha-1B-glycoprotein

A1BG

0.197

(0.070)

0.211

(0.104)

0.914

57127/6.89

76

84,85

signal transduction

Rab GDP dissociation inhibitor alpha

GDIA

0.403

(0.118)

0.440

(0.112)

0.829

50504/5.00

73

122

stress response

Heat shock-related 70 kDa protein 2

HSP72

0.084

(0.031)

0.100

(0.024)

0.738

69599/5.51

115

4,5

transport

Serum albumin

ALBU

3.629

(1.939)

4.722

(1.882)

0.722

70682/6.09

306

40

transport

Aspartate aminotransferase

AATM

0.246

(0.070)

0.165

(0.041)

0.387

47683/9.13

64

55

transport

3-mercaptopyruvate sulfurtransferase

THTM

0.053

(0.014)

0.047

(0.046)

0.893

33205/5.88

75

108

transport

Clathrin light chain B

CLCB

0.310

(0.090)

0.324

(0.156)

0.953

25216/4.65

63

127

transport

V-type proton ATPase catalytic subunit A

VATA

0.056

(0.028)

0.057

(0.027)

0.982

68283/5.42

77