The effect of SBG on LPS induced PGE2 and NO production with the Raw 264.7 cells and BV2 cells. Raw 264.7 cells (A) and BV2 cells (B) were pretreated with the indicated concentrations of SBG for 30 min before incubation with LPS for 24 h. The culture supernatants were subsequently isolated and analyzed for nitrate levels. Values are expressed as mean ± standard deviation (mean ± S.D.), and analyzed by one-way ANOVA and multiple comparisons were performed by Tukey HSD test. A criterion of significance was accepted and marked as P < 0.001 (###). The mark of star is AC group versus NC group and the mark of pound is each treatment group versus AC group.