PKG inhibition by KT5823 augments single channel SOC activity. Using cell attached patch clamp electrophysiology, single channel SOC activity in PASMCs was assessed (holding potential, -80 mV) in the absence and presence of 3 μM KT5823. Representative traces and summary data can be found in A &B, respectively. Data are means ± SE, n = 6. * denotes significant difference from control.