Figure 3
From: Protein kinases modulate store-operated channels in pulmonary artery smooth muscle cells
PKG inhibition by KT5823 augments single channel SOC activity. Using cell attached patch clamp electrophysiology, single channel SOC activity in PASMCs was assessed (holding potential, -80 mV) in the absence and presence of 3 μM KT5823. Representative traces and summary data can be found in A &B, respectively. Data are means ± SE, n = 6. * denotes significant difference from control.