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Figure 2 | Journal of Biomedical Science

Figure 2

From: Identification of novel DNA methylation inhibitors via a two-component reporter gene system

Figure 2

Identification of optimal DNA demethylating agents. (A) Chemical structures of procainamide, the three selected agents IM25, CI-4-1, and 4e and their structurally related analogues IM9, CI-5-1, and 4o. (B) Potencies of procainamide, IM25, IM9, C-4-1, CI-5-1, 4e, and 4o in attenuating EGFP expression in the two-component reporter system. The EGFP intensities in individual treatments are illustrated on the right. Columns, mean (n = 3); error bars, S.D.

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