|
Experimental groups
|
Cerebellum
|
Brain stem
|
|---|
|
B
max
(fmoles/mg protein)
|
K
d
(nM)
|
B
max
(fmoles/mg protein)
|
K
d
(nM)
|
|---|
|
Control
|
71.50 ± 2.41
|
11.11 ± 0.95
|
153.36 ± 3.7
|
4.77 ± 0.44
|
|
Hx
|
50.01 ± 1.80 a
|
14.82 ± 0.82 a
|
116.68 ± 2.8 a
|
3.77 ± 0.22 a
|
|
Hx + G
|
62.18 ± 1.50 b
|
9.85 ± 0.36 b
|
173.36 ± 2.5 b
|
6.78 ± 0.35 a, b
|
|
Hx + G + O
|
66.33 ± 2.00 b
|
12.54 ± 0.42
|
160.84 ± 3.4 b
|
5.01 ± 0.26 a, b
|
|
Hx + O
|
55.34 ± 2.50 a
|
15.72 ± 0.54 a
|
136.68 ± 2.3 a, b
|
4.73 ± 0.29 b
|
|
Hx + E
|
44.02 ± 3.20 a
|
10.46 ± 0.10 b
|
122.08 ± 2.6 a
|
3.30 ± 0.14 a
|
|
Hx + G + E + O
|
45.50 ± 2.50 a
|
7.46 ± 0.11a, b
|
125.84 ± 4.5 a
|
4.10 ± 0.22 b
|
- Values are Mean ± S.E.M of 4-6 separate experiments. Each group consist 6-8 neonatal rats.
- a p < 0.001 when compared with control
- b p < 0.001 when compared with hypoxic group.
- Hypoxic rats- Hx, Hypoxic rats glucose treated - Hx+G, Hypoxic rats oxygen treated - Hx+O, Hypoxic rats glucose and oxygen treated - Hx+G+O, Hypoxic rats epinephrine treated - Hx + E, Hypoxic rats glucose, epinephrine and oxygen treated - Hx+G+E+O
