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Table 1 The ten most upregulated and down regulated primary epithelial genes in response to stroma, in 3D culture

From: Stromal upregulation of lateral epithelial adhesions: Gene expression analysis of signalling pathways in prostate epithelium

Gene Symbol Gene Title Fold change Probe ID
FGFBP1 fibroblast growth factor binding protein 1 3.078 H300006842
OR4N5 olfactory receptor, family 4, subfamily N, member 5 2.993 opHsV0400002653
KLRC4 killer cell lectin-like receptor subfamily C, member 4 2.735 H300021805
TESSP1 testis serine protease 1 2.656 opHsV0400002778
KT3K Ketosamine-3-kinase 2.528 H200004088
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.420 H200005914
SNX12 sorting nexin 12 2.330 H200009199
PABPC1 poly(A) binding protein, cytoplasmic 1 2.323 H200014179
DNMBP Dynamin binding protein 2.282 opHsV0400003719
MSH4 mutS homolog 4 2.265 H200011946
IL23R interleukin 23 receptor -2.489 H300020818
DYNC2LI1 dynein 2 light intermediate chain isoform 1 -2.553 opHsV0400000277
KRT6B keratin 6B -2.560 H300014335
SAA1 serum amyloid A1 -2.600 opHsV0400005893
TOP1 topoisomerase (DNA) I -2.844 opHsV0400006965
PTPLAD1 protein tyrosine phosphatase domain containing 1 -2.859 H300003447
SEMA3C sema domain, secreted 3C -3.412 H200008006
KRT23 keratin 23 -3.552 H300014341
C3 complement component 3 -3.553 H20000880
MAGI1 membrane associated guanylate kinase, WWW and PDZ domain containing 1 -4.678 H200002533
  1. Values are the mean fold expression changes of ten primary epithelial cell cultures, abstracted from Operon datasets. All genes showed significant differential expression (p < 0.05). Positive values indicate up regulation, negative values indicate down regulation of epithelial genes cultured with stroma compared to without stroma. Hypothetical or unassigned genes were removed from the list.